FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to a chimeric antigen receptor (hereinafter – CAR), which binds to Fc receptor-like protein 5 (hereinafter – FcRL5), as well as to a composition and a kit containing it. A nucleic acid molecule encoding the above-mentioned CAR is also disclosed, as well as a cell and a vector containing it.
EFFECT: invention is effective for the treatment of tumor expressing FcRL5.
92 cl, 27 dwg, 240 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CHIMERIC ANTIGEN RECEPTORS TARGETING CD70 | 2019 |
|
RU2801824C2 |
| T-CELL RECEPTORS | 2017 |
|
RU2775623C2 |
| IL4/IL13 RECEPTOR MOLECULE FOR VETERINARY USE | 2018 |
|
RU2795591C2 |
| CHIMERIC ANTIGEN RECEPTOR | 2018 |
|
RU2770002C2 |
| CHIMERIC ANTIGENE RECEPTORS TARGETTING FLT3 | 2018 |
|
RU2820859C2 |
| CHIMERIC ANTIGEN RECEPTORS AND BINDING AGENTS TARGETING DLL3 | 2020 |
|
RU2822366C2 |
| T-CELL RECEPTOR CONSTRUCTS AND THEIR USE | 2019 |
|
RU2785954C2 |
| IMPROVED SYNTHETIC T-CELL RECEPTOR AND ANTIGEN RECEPTOR | 2021 |
|
RU2820497C1 |
| ANTIBODIES DIRECTED AGAINST Fc-RECEPTOR-LIKE PROTEIN 5 AND METHODS FOR THEIR APPLICATION | 2016 |
|
RU2774158C2 |
| CHIMERIC CYTOKINE RECEPTOR | 2016 |
|
RU2826122C1 |
