FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to polynucleotide encoding factor IX protein; it can be used in medicine. Polynucleotide contains a nucleic acid sequence that is at least 99% identical to a nucleic acid sequence SEQ ID NO: 17.
EFFECT: obtained polynucleotide can be used in the composition of a vector for effective gene therapy of hemophilia B in mammals.
26 cl, 25 dwg, 7 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| IX PADUA FACTOR ANTIBODIES | 2017 |
|
RU2770006C2 |
| INFLUENZA HAEMAGGLUTININ AND NEURAMINIDASE VARIANTS | 2010 |
|
RU2535970C2 |
| USE OF LENTIVIRAL VECTORS EXPRESSING IX FACTOR | 2019 |
|
RU2816873C2 |
| VERSIONS OF HEMAGGLUTININ AND NEURAMINIDASE OF INFLUENZA VIRUS | 2009 |
|
RU2523587C2 |
| MODIFIED FACTOR IX, AS WELL AS COMPOSITIONS, METHODS AND OPTIONS FOR THE USE OF GENE TRANSFER INTO CELLS, ORGANS AND TISSUE | 2016 |
|
RU2811445C2 |
| LYSE VARIANT AND METHOD FOR PRODUCING L-ARGININE USING SAME | 2022 |
|
RU2840267C2 |
| CODON-OPTIMIZED NUCLEIC ACID WHICH CODES BLOOD COAGULATION FACTOR IX PROTEIN, AND USE THEREOF | 2021 |
|
RU2831751C2 |
| NUCLEIC ACID MOLECULES AND WAYS OF USING THEM | 2018 |
|
RU2819144C2 |
| NUCLEIC ACID MOLECULES AND WAYS OF USING THEM FOR NON-VIRAL GENE THERAPY | 2019 |
|
RU2834625C2 |
| ARTIFICIAL NUCLEIC ACID MOLECULES | 2013 |
|
RU2651498C2 |
