FIELD: biotechnology.
SUBSTANCE: disclosed is a polypeptide involved in the production of l-arginine, having 80 % or more sequence identity with SEQ ID NO: 1, and wherein any one or more amino acids from amino acids corresponding to positions 50, 153 and 215 in SEQ ID NOs: 1, is replaced with another amino acid, where the amino acid corresponding to position 50 is replaced with valine, leucine or isoleucine, the amino acid corresponding to position 153 is replaced with serine, threonine or glutamine, the amino acid corresponding to position 215 is substituted with serine, threonine or glutamine. Also disclosed are a polynucleotide encoding said polypeptide, a Corynebacterium microorganism for producing L-arginine, containing said polypeptide or polynucleotide encoding said polypeptide, and method of producing L-arginine.
EFFECT: invention increases output of L-arginine.
8 cl, 5 tbl, 3 ex
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