FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to an antibody for specific binding with an interleukin 4 (IL-4) receptor (IL-4R). A nucleic acid molecule encoding the specified antibody; an expression vector, a host cell, containing the specified nucleic acid molecule; a pharmaceutical composition, fused protein, and conjugate, containing the specified antibody, are also disclosed. A method for the production of the specified antibody; the use of the specified antibody, fused protein or conjugate for the manufacture of a drug; a method for the treatment, prevention or relief of severity of an inflammatory or allergic disease, using the specified antibody, are disclosed.
EFFECT: invention has a capability of effective treatment of diseases associated with interleukin 4 (IL-4) receptor (IL-4R).
32 cl, 5 dwg, 15 tbl, 10 ex
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Authors
Dates
2022-06-21—Published
2017-06-08—Filed