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(19)

(11)

2 812 200

(13)

(51)

IPC

C07K16/28(2006-01-01)

A61K39/395(2006-01-01)

A61K47/68(2017-01-01)

C12N15/85(2006-01-01)

C12N5/10(2006-01-01)

C12P21/08(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2021109816, 2019-09-11

(24)

Start date

2019-09-11

(22)

Actual filing date

2019-09-11

(45)

Published

2024-01-25

(72)

Inventor

Yang, YiXie, JingshuDong, ChunyanYang, FangLu, ChengyuanShen, YueleiNi, JianGuo, YananChen, Yunyun

(73)

Holder

Eucure Biopharma Co., Ltd

ANTIBODIES AGAINST TNFRSF9 AND THEIR USE Russian patent published in 2024 - IPC C07K16/28 A61K39/395 A61K47/68 C12N15/85 C12N5/10 C12P21/08 A61P35/00

Abstract RU 2812200 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to an antibody or its antigen-binding fragment that binds to 4-1BB. Also the following is disclosed: the use of the above antibody or an antigen binding fragment thereof to produce a bispecific antibody.

EFFECT: invention is effective for the treatment of cancer.

15 cl, 83 dwg, 49 tbl, 21 ex

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RU 2 812 200 C2

Authors

Yang, Yi

Xie, Jingshu

Dong, Chunyan

Yang, Fang

Lu, Chengyuan

Shen, Yuelei

Ni, Jian

Guo, Yanan

Chen, Yunyun

Dates

2024-01-25—Published

2019-09-11—Filed