METHOD FOR PREDICTION OF DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE Russian patent published in 2022 - IPC G01N33/50 

FIELD: medicine; therapy; pulmonology; nephrology.

SUBSTANCE: invention relates to medicine, namely to therapy, pulmonology, nephrology; it can be used in the prediction of the development of chronic kidney disease (hereinafter – CKD) in individuals with chronic obstructive pulmonary disease (hereinafter – COPD). To do this, the patient’s quality of life is assessed in points by filling out the COPD Assessment Test questionnaire, the severity of dyspnea is assessed in points according to the British Medical Research Council scale, a number of exacerbations suffered by the patient over the previous 12 months is calculated, a level of leukocytes, concentration of chlorine ions, interleukin-6 and tumor necrosis factor α in the blood serum is determined. Then, three classifying discriminant equations are solved. Obtained results Y1, Y2, and Y3 are compared, and, if the maximum value is Y1, then, the patient with COPD is predicted to have a high probability of the development of CKD with a glomerular filtration rate (hereinafter – GFR)<60 ml/min/1.73 m². If the maximum value is Y2, then the patient with COPD is predicted to have a high probability of the development of CKD with GFR≥60 ml/min/1.73 m². If the maximum value is Y3, then the patient with COPD has no probability of the development of CKD.

EFFECT: method provides prediction of the probability of the development of CKD in individuals with COPD, based on an assessment of clinical and laboratory characteristics of COPD, which makes it possible to start preventive measures at an earlier stage, within 8 hours, preventing the development and further progression of CKD.

1 cl, 3 ex