ANTIBODY-DRUG CONJUGATE Russian patent published in 2022 - IPC C07K16/28 A61K39/395 A61P35/00 A61K31/4745 A61K31/48 

Abstract RU 2776489 C2

FIELD: biotechnology.

SUBSTANCE: group of inventions is described, including a compound of HO-CH2-C(=O)-(NH-DX) and the use of a compound of HO-CH2-C(=O)-(NH-DX) for the treatment of tumor or cancer selected from lung cancer, kidney cancer, urothelial cancer, colorectal cancer, prostate cancer, glioblastoma multiforme, ovarian cancer, pancreatic cancer, breast cancer, melanoma, liver cancer, bladder cancer, stomach cancer or esophageal cancer.

EFFECT: invention expands the arsenal of anti-inflammatory and anticancer remedies.

3 cl, 22 dwg, 97 ex

Similar patents RU2776489C2

Title Year Author Number
ANTI-HER3 CONJUGATE ANTIBODY-DRUG 2015
  • Hettmann, Thore
  • Abraham, Reimar
  • Blum, Sabine
  • Ueno, Suguru
RU2802211C2
ANTI-TROP2 ANTIBODY-DRUG CONJUGATE 2014
  • Agatsuma, Tosinori
  • Takakhasi, Su
  • Khasegava, Dzun
  • Okadzima, Daisuke
  • Khamada, Khirofumi
  • Yamaguti, Miki
RU2743077C2
ANTI-CDH6-ANTIBODY AND ANTI-CDH6-ANTIBODY-DRUG CONJUGATE 2018
  • Saito Atsuko
  • Hirata Tsuyoshi
  • Nakamura Kensuke
RU2798285C2
ANTI-MUC1 DRUG CONJUGATE 2019
  • Gellert, Johanna
  • Flechner, Anke
  • Weigelt, Doreen
  • Danielczyk, Antje
  • Nagase, Akiko
RU2804703C2
ANTIBODY AGAINST GPR20 AND ANTIBODY AGAINST GPR20-DRUG CONJUGATES 2018
  • Iida, Kenji
  • Hirai, Takehiro
  • Terauchi, Tomoko
  • Nakamura, Kensuke
RU2772804C2
ANTI-HER2 ANTIBODY DRUG CONJUGATE 2015
  • Naito, Hiroyuki
  • Ogitani, Yusuke
  • Masuda, Takeshi
  • Nakada, Takashi
  • Yoshida, Masao
  • Ashida, Shinji
  • Morita, Koji
  • Miyazaki, Hideki
  • Kasuya, Yuji
  • Hayakawa, Ichiro
  • Abe, Yuki
RU2794183C2
CONJUGATE ANTIBODY-DERIVATIVE OF PYRROLOBENZODIAZEPINE 2018
  • Kharada, Naoia
  • Ota, Yusuke
  • Doi, Fuminao
  • Meguro, Masaki
  • Khayakava, Itiro
  • Asida, Sintszi
  • Masuda, Takesi
  • Nakada, Takasi
  • Ivamoto, Mitsukhiro
  • Kharada, Naoya
  • Terauti, Tomoko
  • Okatszima, Dajsuke
  • Nakamura, Kensuke
  • Utida, Khiroaki
  • Khamada, Khirofumi
RU2820928C2
SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES 2019
  • Peres, Mishel
  • Marion, Frederik
  • Ev, Zhan-Fransua
  • Drejfyu, Sirill
RU2815199C2
ANTIBODY AND DRUG CONJUGATES FOR DESTRUCTION OF HEMATOPOIETIC STEM CELLS 2017
  • Wen, Ben
  • Boitano, Anthony E.
  • Burger, Matthew
  • Cellitti, Susan E.
  • Cooke, Michael P.
  • Finner, Catrin
  • Geierstanger, Bernhard Hubert
  • Jin, Yunho
  • Lee-Hoeflich, Si Tuen
  • Pham, Hongngoc Thi
  • Schleyer, Siew Ho
  • Tissot, Kathrin
  • Uno, Tetsuo
RU2781444C2
MAITANZINOID DERIVATIVES WITH SELF-SPLITTING PEPTIDE LINKERS AND THEIR CONJUGATES 2018
  • Widdison, Wayne, C.
RU2765098C2

RU 2 776 489 C2

Authors

Masuda, Takeshi

Naito, Hiroyuki

Nakada, Takashi

Yoshida, Masao

Ashida, Shinji

Miyazaki, Hideki

Kasuya, Yuji

Morita, Koji

Abe, Yuki

Ogitani, Yusuke

Dates

2022-07-21Published

2013-10-10Filed