FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a linker of formula (I) or a pharmaceutically acceptable salt thereof, a linker-drug conjugate of formula (II) or a pharmaceutically acceptable salt thereof, a linker-drug conjugate such as an antibody-drug conjugate of formula (III) or (IV) or a pharmaceutically acceptable salt thereof, as well as a pharmaceutical composition including such a binding unit-drug conjugate, and its use for the treatment of cancer.
EFFECT: obtaining sulfomaleimide-based linkers and corresponding conjugates.
19 cl, 28 dwg, 15 tbl, 7 ex
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