FIELD: medicine.
SUBSTANCE: present invention relates to a cobalamin derivative of the formula (I), in which X is ligand with the formula selected from a group consisting of -(CH2)1-5-S-(CH2)0-3-CH3, -S-(CH2)1-5-NH2, 
, where R1 = H, methyl, or ethyl, R2 = 
, and R3 = -H, or 
. A pharmaceutical composition, a food additive, a method for the production of a cobalamin derivative, and its use are also proposed.
EFFECT: proposed cobalamin derivatives of the formula (I) are useful for the treatment of vitamin B12-related disorders caused by either reduced vitamin B12 intake from food to cells that need it, or a genetic defect, or another obstacle in the way of transfer and intracellular recycling of B12.
12 cl, 15 dwg, 6 tbl, 16 ex
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