FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to a nucleic acid molecule, which encodes an anti-4-1BB antibody or its antigen-binding fragment. A recombinant vector containing the specified nucleic acid molecule, and a host cell containing the specified nucleic acid molecule are also disclosed.
EFFECT: invention allows for the effective treatment of diseases associated with 4-1BB factor.
5 cl, 5 ex, 22 dwg, 7 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANTI-HUMAN 4-1BB ANTIBODIES AND USE THEREOF | 2018 |
|
RU2725811C1 |
| ANTIBODIES AGAINST TNFRSF9 AND THEIR USE | 2019 |
|
RU2812200C2 |
| ANTIBODIES AGAINST HUMAN VSIG4 AND APPLICATION THEREOF | 2019 |
|
RU2776638C1 |
| NK-CELL ACTIVATING FUSED PROTEIN, NK-CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | 2018 |
|
RU2740438C1 |
| ANTIBODIES AGAINST OX40 AND THEIR USE | 2017 |
|
RU2783314C2 |
| ANTI-αvβ8 ANTIBODIES AND COMPOSITIONS AND THEIR USE | 2019 |
|
RU2812478C2 |
| ANTIBODIES AGAINST CD40 AND THEIR USE | 2018 |
|
RU2796413C2 |
| NEW ANTI-CD19 ANTIBODIES | 2018 |
|
RU2791445C2 |
| ANTIBODIES TO HUMAN INTERLEUKIN-2 AND THEIR APPLICATION | 2018 |
|
RU2745451C1 |
| ANTIBODIES AGAINST CTLA4 AND THEIR USE | 2017 |
|
RU2779312C2 |
