PHARMACEUTICAL COMPOSITION CONTAINING APL TYPE PEPTIDE Russian patent published in 2022 - IPC A61K38/17 C07K14/47 A61P29/00 

Abstract RU 2778402 C2

FIELD: biotechnology.

SUBSTANCE: pharmaceutical composition containing APL type peptide identified as SEQ ID No.1, a sodium-acetate buffer solution with a pH value of 3.9-4.7, and stabilizing sugar, and its use are presented, as well as a method for the treatment of an inflammatory disease related to an increase in neutrophiles or citrullination of proteins.

EFFECT: invention allows for obtaining a pharmaceutical composition, which can be used for obtaining a drug for the treatment of inflammatory diseases related to an increase in neutrophiles or citrullination of proteins, such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS), Alzheimer’s disease, as well as liver and lung fibrosis.

7 cl, 7 dwg, 3 tbl, 4 ex

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RU 2 778 402 C2

Authors

Dominguez Horta, Maria Del Carmen

Lopez Abad, Cruz Matilde

Gonzalez Lopez, Luis Javier

Besada Perez, Vladimir Armando

Dates

2022-08-18Published

2018-12-21Filed