FIELD: biotechnology.
SUBSTANCE: pharmaceutical composition containing APL type peptide identified as SEQ ID No.1, a sodium-acetate buffer solution with a pH value of 3.9-4.7, and stabilizing sugar, and its use are presented, as well as a method for the treatment of an inflammatory disease related to an increase in neutrophiles or citrullination of proteins.
EFFECT: invention allows for obtaining a pharmaceutical composition, which can be used for obtaining a drug for the treatment of inflammatory diseases related to an increase in neutrophiles or citrullination of proteins, such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS), Alzheimer’s disease, as well as liver and lung fibrosis.
7 cl, 7 dwg, 3 tbl, 4 ex
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Authors
Dates
2022-08-18—Published
2018-12-21—Filed