BLOCKING OF INFLAMMATORY PROTEASES BY THETA-DEFENSINS Russian patent published in 2018 - IPC A61K38/10 A61K38/12 A61P19/02 A61P29/00 

Abstract RU 2652605 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely, to treatment of inflammatory diseases mediated by TNF-alpha, and concerns the blocking of inflammatory proteases by theta-defensins. Effective amount of theta-defensin is administered, which is selected from the group that consists of the following items RTD-1, RTD-2, RTD-3, RTD-4, RTD-5, RTD-1-27, RTD-1-28 and RTD-1-29.

EFFECT: provides for the effective treatment due to competitive inhibition by means of the stated activity compounds of the TNF-alpha converting enzyme (TACE).

6 cl, 9 dwg, 7 ex

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RU 2 652 605 C2

Authors

Selsted Majkl E.

Tran Dat K.

Shaal, Dzhastin B.

Dates

2018-04-27Published

2012-06-01Filed