EYE DROPS IN FORM OF SOLUTION CONTAINING BENZOPYRAN DERIVATIVE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT Russian patent published in 2022 - IPC A61K9/08 A61K31/4178 A61K47/10 A61K47/18 A61P27/02 

Abstract RU 2778515 C2

FIELD: medicine; ophthalmology.

SUBSTANCE: group of inventions relates to the field of medicine, namely to ophthalmology; it is intended for prevention or treatment of degenerative processes of the macula. An eye drop composition in the form of a solution contains (2R, 3R, 4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazole-2-ylmethyl)amino]-3-hydroxy-2-methyl-2-dimethoxymethyl-3,4-dihydro-2H-1-benzopyran or its pharmaceutically acceptable salt, propylene glycol as a stabilizing agent, and a pH-regulating agent in an aqueous medium. The specified components are used in the claimed amounts. The eye drop composition has pH in the range from 4.0 to 5.0. A pharmaceutical product for the prevention or treatment of degenerative processes of the macula is also presented, obtained by placement of the specified eye drop composition to a light-impermeable container.

EFFECT: use of the group of inventions allows for an increase in the stability of an eye drop composition.

14 cl, 2 dwg, 17 tbl, 13 ex

Similar patents RU2778515C2

Title Year Author Number
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT MACULAR DEGENERATION 2012
  • Yi Kyu-Yang
  • Yoo Sung-Eun
  • Kim Nack-Jeong
  • Suh Jee-Hee
  • Joo Choun-Ki
  • Choi Jun-Sub
  • Yang Jae-Sik
  • Lee Geun-Hyeog
  • Cho Yun-Seok
  • Park Jin-Ha
  • Lee Hye-Sung
RU2576380C2
METHOD OF PURIFYING A BENZOPYRAN DERIVATIVE, ITS CRYSTALLINE FORM AND A METHOD OF PRODUCING A CRYSTALLINE FORM 2016
  • Ryu Jae-Chun
  • Park Yong-Kyun
  • Kim Hyun-Kyu
  • Shin Dong-Yeop
RU2729074C2
DERIVATIVES OF BENZOPYRANE SUBSTITUTED WITH SECONDARY AMINES COMPRISING TETRAZOLE, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF 2003
  • Lim Khong
  • Li Dong-Kha
  • Kim Sun-Ok
  • Choj In-Joung
  • Joo Sung-Eun
  • Ji Kiju-Jang
  • Li Sun-Kijung
  • Sukh Dzi-Khi
  • Kim Nak-Dzeong
  • Li Bijung-Kho
  • Seo Kho-Von
  • Shin Khva-Sup
RU2283312C2
STABLE COMPOSITION INCLUDING EPIDERMIC GROWTH FACTOR (EGF) AS ACTIVE INGREDIENT 2001
  • Jang Dzeong-Khva
  • Li Dzang-Von
  • Shon Mi-Jang
  • Kim Jang-Dzun
RU2222344C2
PHARMACEUTICAL COMPOSITIONS CONTAINING BISPHOSPHONATE DERIVATIVES AND HIGH DOSES OF CHOLECALCIFEROL 2010
  • Kim Jin-Sun
  • Lee Geun-Hyeog
  • Choi Byong-Sun
  • Kim Jae-Shin
  • Park Jin-Ha
  • O Mi-Jin
  • Kim Eun-Mi
RU2533230C2
OPHTHALMIC DROPS COMPOSITION 2012
  • Goris Nesia
  • Nejts Jokhan
  • Blomsma Ervin
  • Vera Stefan
  • Billit Ajno
  • Auerks Yuri
  • Deberme Veerle
  • Ro Marilin
  • Pyuizh Paskal
RU2623066C2
OPHTHALMIC FORMULATIONS FOR DRUG DELIVERY TO THE POSTERIOR SEGMENT OF THE EYE 2014
  • Bingaman, David, P.
  • Chaney, Paul, G.
  • Wax, Martin, B.
RU2768489C2
LIQUID COMPOSITION OF LONG-ACTING INSULIN AND INSULINOTROPIC PEPTIDE 2013
  • Lim Hyung Kyu
  • Kim Hyun Uk
  • Lee Mi Kyoung
  • Lee Jong Soo
  • Bae Sung Min
  • Kwon Se Chang
RU2643766C2
OCULAR COMPOSITIONS FOR DRUG-DELIVERY TO POSTERIOR SEGMENT OF THE EYE 2014
  • Bingamen Devid P.
  • Chejni Pol G.
  • Uaks Martin B.
RU2665953C2
OPHTHALMIC COMPOSITION CONTAINING CYCLOSPORINE AND TREHALOSE 2015
  • Um, Key-An
  • Kim, Yeong-Mok
  • Hwang, Deok-Kyu
  • Ahn, Mi Sun
  • Nam, Seung Kwan
  • Ko, Dae Woong
  • Hong, Sung-Woon
  • Lim, Jong Hwan
RU2700927C2

RU 2 778 515 C2

Authors

Shin Dong-Yeop

Kim Hu-Seong

Lee Geun-Hyeog

Kim Kyung-Joon

Cho Yun-Seok

O Mi-Jin

Kim Mi-Jung

Dates

2022-08-22Published

2019-02-18Filed