FIELD: chemistry.
SUBSTANCE: present invention is aimed at the provision of a preparation, which, as it is expected, will improve a bitter taste of salt of organic vonoprazan acid and provide a possibility of fast dissolution of salt of organic vonoprazan acid after the administration. The present invention provides for a preparation containing fine granules or granules containing (1) a core granule containing salt of organic vonoprazan acid, (2) an intermediate layer containing the same organic acid as organic acid forming vonoprazan salt in (1), or its salt, and (3) a coating layer containing water-insoluble polymer.
EFFECT: obtaining a preparation for improvement of a taste and provision of a possibility of fast dissolution of salt of organic vonoprazan acid.
11 cl, 26 ex, 4 tbl, 16 dwg
