FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a compound being a derivative of pyrido[3,4-d]pyrimidine-8-one, exhibiting an excellent antiproliferative effect against cancer cells, and to a pharmaceutically acceptable salt thereof, as well as to a pharmaceutical composition for preventing, alleviating, or treating cancer caused by an NRAS (gene encoding the Ras protein, small G-protein) mutation, containing the above compound as an active ingredient.
EFFECT: production of a composition for preventing, alleviating, or treating cancer.
10 cl, 3 ex, 2 tbl
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