FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to diagnostics of Gaucher’s disease. A method for identification of an individual suitable for the therapy suitable for the treatment of Gaucher’s disease in him/her includes testing of a sample from the individual for the presence of a biomarker – free lyso-Gb1, where the individual is suitable for the therapy, if the results of sample testing are positive relatively to the biomarker, where the testing results are positive relatively to the biomarker, if a level of the biomarker in the individual’s sample exceeds the threshold level. A method for the treatment of Gaucher’s disease in an individual includes testing of a sample from the individual for the presence of a biomarker.
EFFECT: above-described methods allow for increase in the general therapeutic efficiency in the treatment of Gaucher’s disease.
17 cl, 12 dwg, 6 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIAGNOSIS OF GAUCHER'S DISEASE | 2012 |
|
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| COMPOSITIONS AND METHODS FOR TREATING GAUCHER DISEASE | 2010 |
|
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| COMPOSITIONS AND METHODS FOR TREATING GAUCHER DISEASE | 2010 |
|
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| METHOD FOR NUCLEOSOMES ADDUCTS DETECTION | 2012 |
|
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|
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| BIOMARKERS OF METHOTREXATE-INDUCED IMMUNE TOLERANCE | 2018 |
|
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| PROGNOSTIC METHOD FOR INDIVIDUALS WITH PROSTATE CANCER | 2013 |
|
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| METHODS OF DIAGNOSIS AND COMPOSITION FOR CANCER TREATMENT | 2013 |
|
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| BIOMARKERS PREDICTING A THERAPEUTIC RESPONSE TO THERAPY WITH A CHIMERIC ANTIGEN RECEPTOR, AND USE THEREOF | 2015 |
|
RU2743657C2 |
| ANTIBODY ANALYSIS | 2017 |
|
RU2769987C2 |
