METHOD FOR TREATMENT OF MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN ASSOCIATED WITH SARS-CoV-2 Russian patent published in 2022 - IPC A61M1/34 G01N33/48 A61K38/38 A61K31/573 A61P31/00 

Abstract RU 2780939 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to intensive care, infectious diseases and pediatrics. Patients are prescribed complex drug therapy in combination with a course of therapeutic plasmapheresis (PA) lasting from two to five sessions with a frequency of 1 every two days with the intake of circulating plasma in the amount of 30-60% and replacement of the excreted plasma with crystalloid solutions. In particular cases, with values of C-reactive protein in the blood of 100 or more, pulse therapy with methylprednisolone in the amount of 10-30 mg/kg is performed once a day for three days before the course of PA. In a particular case, with indications of hypoalbuminemia of less than 25 g/l, the replacement of the excreted plasma is performed with crystalloid solutions and additionally with an albumin solution. At the same time, in particular cases, the calculation of the volume of circulating plasma is carried out according to the formula.

EFFECT: invention provides an expansion of the arsenal of methods for the treatment of MIS in children associated with SARS-CoV-2, contributes to a more favorable course of diseases, especially difficult to treat with medication, provides a significant improvement in the condition of patients and reduces the drug load.

4 cl, 3 ex

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RU 2 780 939 C1

Authors

Sabinina Tatiana Sergeevna

Melekhina Elena Valerievna

Novikov Dmitrii Valerevich

Fedorov Pavel Vladimirovich

Trunova Ekaterina Alekseevna

Mirzonov Vladislav Aleksandrovich

Akimkin Vasilii Gennadevich

Dates

2022-10-04Published

2021-12-22Filed