FIELD: biotechnology.
SUBSTANCE: present invention relates to the field of biotechnology, in particular, to a new antibody specifically binding to lysyl-tRNA synthetase, usable in medicine. More specifically, the invention allows for an antibody capable of specifically binding to the N-terminal domain of the lysyl-tRNA synthetase enzyme (KRS, lysyl-tRNA synthetase) exposed on extracellular membrane.
EFFECT: antibody can be used in treating or diagnosing cancer, metastases in cancer, or diseases associated with immune cell migration.
26 cl, 13 ex, 13 tbl, 19 dwg
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION CONTAINING AN ANTIBODY SPECIFICALLY BINDING WITH THE N-TERMINAL OF LYSYL-TRNA SYNTHETASE AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF DISEASES CAUSED BY CELL MIGRATION | 2018 |
|
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Authors
Dates
2022-10-11—Published
2019-09-17—Filed