PHARMACEUTICAL COMPOSITION FOR PRODUCING A LYOPHILISATE OF LIVER CELL CULTURE ENRICHED WITH HEPATOCYTE GROWTH FACTOR Russian patent published in 2022 - IPC A61K35/48 A61K35/54 A61K35/407 C12N5/73 

Abstract RU 2781448 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry, namely, to production of a pharmaceutical composition for producing a lyophilisate enriched with prolonged-action hepatocyte growth factor (HGF), stimulating the proliferation of liver hepatocytes. Pharmaceutical composition for producing a lyophilisate enriched with prolonged-action hepatocyte growth factor (HGF), stimulating the proliferation of liver hepatocytes, containing a cell population, characterised by using a neonatal rat liver cell culture as a cell population and a source of HGF, and solutions of polyvinylpyrrolidone, sucrose, and albumin are used as a structure-forming agent and prolongator, at a certain ratio of components.

EFFECT: above solution provides a possibility of producing a lyophilisate agent stimulating liver regeneration.

1 cl, 4 dwg, 1 tbl, 2 ex

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RU 2 781 448 C1

Authors

Inozemtsev Pavel Olegovich

Lepekhova Svetlana Aleksandrovna

Kostyro Yana Antonovna

Makoshina Polina Sergeevna

Goldberg Oleg Aronovich

Dates

2022-10-12Published

2021-08-18Filed