FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to a guide RNA molecule of the CRISPR-Cas system, a ribonucleoprotein complex of the CRISPR-Cas system containing the above molecule, as well as kits containing a ribonucleoprotein complex of the CRISPR-Cas system and specific oligonucleotides for preliminary amplification of a highly conserved region of the hepatitis virus genome C.
EFFECT: invention allows efficient detection of hepatitis B virus DNA after specific amplification of a fragment of the genome of this virus; invention provides detection of single copies of hepatitis B virus DNA.
7 cl, 13 dwg, 5 tab, 7 ex
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