FIELD: organic chemistry.
SUBSTANCE: invention relates to the field of organic chemistry, namely to a compound of the class 3-aroyl-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2 -a]quinoxaline-1,4(3aH,5H)-diones, which can be used as starting products for the synthesis of new heterocyclic systems and in pharmacology. The invention relates to 3-(4-chlorobenzoyl)-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2-a]quinoxalin- 1,4(3aH,5H)-dione. The compound of the invention is obtained by reacting 3-(4-chlorobenzoyl)pyrrolo[1,2-a]quinoxaline-1,2,4(5H)-trione with 5,5-dimethylcyclohexane-1,3-dione in a solvent medium, with subsequent isolation of the target products. Anhydrous acetonitrile is used as the solvent.
EFFECT: 3-(4-chlorobenzoyl)-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2-a]quinoxalin-1,4 (3aH,5H)-dione with antimicrobial activity.
3 cl, 1 bl, 2 ex
| Title |
Year |
Author |
Number |
| APPLICATION (R*)-3-(4-CHLOROBENZOYL)-2-HYDROXY-3А-(R*)-2-OXOINDOLIN-3-YL)-5-PHENYLPYRROLO [1,2-A]QUINOXALIN-1,4(3АH,5H)-DIONE AS ANTIMICROBIAL AGENT |
2021 |
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- Topanov Pavel Andreevich
|
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2018 |
- Maslivets Andrej Nikolaevich
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|
RU2665060C1 |
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2022 |
- Mashevskaia Irina Vladimirovna
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|
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- Mashevskaia Irina Vladimirovna
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- Balandina Svetlana Iurevna
|
RU2783287C1 |
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2015 |
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|
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2023 |
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