3-(4-CHLOROBENZOYL)-2-HYDROXY-3a-(2-HYDROXY-4,4-DIMETHYL-6-OXOCYCLOHEX-1-en-1-yl)PYRROLO[1,2-a]QUINOXALIN-1,4 (3aH,5H)-DIONE WITH ANTIMICROBIAL ACTIVITY AND METHOD FOR ITS PRODUCTION Russian patent published in 2022 - IPC C07D487/04 A61K31/4985 A61P31/00 

Abstract RU 2783264 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely to a compound of the class 3-aroyl-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2 -a]quinoxaline-1,4(3aH,5H)-diones, which can be used as starting products for the synthesis of new heterocyclic systems and in pharmacology. The invention relates to 3-(4-chlorobenzoyl)-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2-a]quinoxalin- 1,4(3aH,5H)-dione. The compound of the invention is obtained by reacting 3-(4-chlorobenzoyl)pyrrolo[1,2-a]quinoxaline-1,2,4(5H)-trione with 5,5-dimethylcyclohexane-1,3-dione in a solvent medium, with subsequent isolation of the target products. Anhydrous acetonitrile is used as the solvent.

EFFECT: 3-(4-chlorobenzoyl)-2-hydroxy-3a-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)pyrrolo[1,2-a]quinoxalin-1,4 (3aH,5H)-dione with antimicrobial activity.

3 cl, 1 bl, 2 ex

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RU 2 783 264 C1

Authors

Mashevskaia Irina Vladimirovna

Topanov Pavel Andreevich

Balandina Svetlana Iurevna

Dates

2022-11-10Published

2022-02-28Filed