METHOD OF PRODUCING 3-AROYL-3A-(3,4-DIHYDRO-2H-PYRAN-5-YL)-2-HYDROXYPYRROLO[1,2-A]QUINOXALINE-1,4 (3AH, 5H)-DIONES Russian patent published in 2016 - IPC C07D487/02 

Abstract RU 2581268 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of obtaining novel 3-aroyl-3a-(3,4-dihydro-2H-pyrane-5-yl)-2-hydroxypyrrolo [1,2-a]quinoxaline-1,4(3aH,5H)-diones of formula I, which consists in fact that 3-aroylpyrrolo[1,2-α]quinoxaline-1,2,4(5H)-triones reacts with 3,4-dihydro-2H-pyrane in inert aprotic solvent, followed by extraction of target products.

EFFECT: these compounds can be used as initial products for synthesis of novel heterocyclic systems and in pharmacology.

2 cl, 1 tbl

I

Similar patents RU2581268C1

Title Year Author Number
METHOD OF PRODUCING 9-ARYL-6,8-DIOXA-13,20-DIAZAPENTACYCLO [11.8.0.0.0.0]HENEICOSA-9,14,16,18-TETRAENE-11,12,21-TRIONES 2015
  • Maslivets Andrej Nikolaevich
  • Makhmudov Ramiz Ragibovich
  • Stepanova Ekaterina Evgenevna
RU2581271C1
METHOD FOR PRODUCING (R*)-3-AROYL-2-HYDROXY-2-((S*)-2-OXOCYCLOALKYL)PYRROLO[1,2-A]QUINOXALINE-1,4(2H,5H)-DIONES 2018
  • Maslivets Andrej Nikolaevich
  • Kasatkina Svetlana Olegovna
  • Stepanova Ekaterina Evgenevna
  • Balandina Svetlana Yurevna
RU2665060C1
3-(4-CHLOROBENZOYL)-2-HYDROXY-3a-(2-HYDROXY-4,4-DIMETHYL-6-OXOCYCLOHEX-1-en-1-yl)PYRROLO[1,2-a]QUINOXALIN-1,4 (3aH,5H)-DIONE WITH ANTIMICROBIAL ACTIVITY AND METHOD FOR ITS PRODUCTION 2022
  • Mashevskaia Irina Vladimirovna
  • Topanov Pavel Andreevich
  • Balandina Svetlana Iurevna
RU2783264C1
16-ALKOXY-14-ARYL-15-OXA-3,10-DIAZATETRACYCLO [8.7.0.0.0]HEPTADECA-4,6,8,13-TETRAENE-2,11,12-TRIONES AND METHOD FOR PRODUCING THEM 2013
  • Stepanova Ekaterina Evgen'Evna
  • Maslivets Andrej Nikolaevich
  • Makhmudov Ramiz Ragibovich
RU2556999C2
3-(2-ARYL-2,4-DIHYDROXY-1(2-HYDROXYETHYL)-5-OXO-2,5-DIHYDRO-1H-PYRROL-3-YL)QUINOXALINE-2(1H)-ONES HAVING ANALGESIC ACTIVITY AND A METHOD FOR PRODUCTION THEREOF 2019
  • Tretyakov Nikita Alekseevich
  • Maslivets Andrej Nikolaevich
  • Makhmudov Ramiz Ragibovich
  • Maslivets Anna Andreevna
RU2707196C1
9-ARYL-6,8,20-TRIOXA-13-AZAPENTACYCLO[11,8,0,01,10,02,7014,19]HENEICOSA-9,14,16,18-TETRAENE-11,12,21-TRIONES AND METHOD FOR PRODUCTION THEREOF 2013
  • Stepanova Ekaterina Evgen'Evna
  • Maslivets Andrej Nikolaevich
  • Makhmudov Ramiz Ragibovich
RU2556998C2
3-AROYL-2-HYDROXY-2-(2-OXOCYCLOALKYL)PYRROLO[2,1-C][1,4]BENZOXAZINE-1,4(2H)-DIONES HAVING ANALGESIC ACTIVITY AND METHODS FOR PRODUCTION THEREOF 2014
  • Maslivets Andrej Nikolaevich
  • Stepanova Ekaterina Evgen'Evna
  • Makhmudov Ramiz Ragibovich
RU2564440C1
METHOD OF OBTAINING 1,2-DIHYDRO-3H-PYRIMIDO[1,6-A]QUINOXALINE-3,5(6H)-DIONES 2018
  • Maslivets Andrej Nikolaevich
  • Kasatkina Svetlana Olegovna
  • Stepanova Ekaterina Evgenevna
  • Makhmudov Ramiz Ragibovich
RU2676682C1
3-AROYL-2-(2-ARYLHYDRAZONO)PYRROLO [1,2-a] QUINOXALINE,4-(2H,5H)DIONES POSSESSING ANALGESIC ACTIVITY 2011
  • Mashevskaja Irina Vladimirovna
  • Kislina Lalita Viktorovna
  • Makhmudov Ramiz Ragibovich
  • Maslivets Andrej Nikolaevich
RU2471798C1
METHOD OF PRODUCING 5-(3-OXO-3,4-DIHYDROQUINOXALIN-2-YL)-2,3-DIHYDRO-4H-1,3-OXAZIN-4-ONES 2019
  • Maslivets Andrej Nikolaevich
  • Kasatkina Svetlana Olegovna
  • Stepanova Ekaterina Evgenevna
  • Makhmudov Ramiz Ragibovich
RU2707194C1

RU 2 581 268 C1

Authors

Maslivets Andrej Nikolaevich

Makhmudov Ramiz Ragibovich

Stepanova Ekaterina Evgenevna

Dates

2016-04-20Published

2015-03-06Filed