FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to A-pentacyclic triterpenoids of general formula: , wherein R=H, R1=
,
or
; R=NH2, R1=
or
.
EFFECT: compounds exhibit antiviral activity, including against type I herpes simplex virus (HSV-1, strain 1 C), HSV-1 and HIV-1, and may be also used as intermediates for new biologically active compounds.
3 cl, 2 tbl, 7 ex
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Authors
Dates
2013-10-27—Published
2012-09-24—Filed