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2 496 785

(13)

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IPC

C07J53/00(2006-01-01)

A61K31/277(2006-01-01)

A61P31/18(2006-01-01)

A61P31/22(2006-01-01)

(21) (22)

Application

2012140905/04, 2012-09-24

(24)

Start date

2012-09-24

(22)

Actual filing date

2012-09-24

(45)

Published

2013-10-27

(72)

Inventor

Grishko Viktorija ViktorovnaTolmacheva Irina Anatol'EvnaGalajko Natal'Ja VladimirovnaBoreko Evgenij IvanovichEremin Vladimir FedorovichSavinova Ol'Ga VladimirovnaKucherov Igor' Ivanovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Institut Tekhnicheskoj Khimii Ural'Skogo Otdelenija Rossijskoj Akademii Nauk Uro Ran)

TRITERPENOIDS WITH EH-NITRILE FRAGMENT IN A-PENTACYCLE Russian patent published in 2013 - IPC C07J53/00 A61K31/277 A61P31/18 A61P31/22

Abstract RU 2496785 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to A-pentacyclic triterpenoids of general formula: , wherein R=H, R₁= , or ; R=NH₂, R₁= or .

EFFECT: compounds exhibit antiviral activity, including against type I herpes simplex virus (HSV-1, strain 1 C), HSV-1 and HIV-1, and may be also used as intermediates for new biologically active compounds.

3 cl, 2 tbl, 7 ex

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RU 2 496 785 C1

Authors

Grishko Viktorija Viktorovna

Tolmacheva Irina Anatol'Evna

Galajko Natal'Ja Vladimirovna

Boreko Evgenij Ivanovich

Eremin Vladimir Fedorovich

Savinova Ol'Ga Vladimirovna

Kucherov Igor' Ivanovich

Dates

2013-10-27—Published

2012-09-24—Filed