SYNTHETIC TETRAPEPTIDE HAEE AND DERIVATIVES THEREOF INTENDED FOR PROTECTION OF HUMAN NEURON FUNCTION Russian patent published in 2024 - IPC A61K38/07 A61P25/00 A61P43/00 

Abstract RU 2822602 C1

FIELD: medicine.

SUBSTANCE: invention refers to neurology and therapy and aims at preventing human neurodegenerative disorders and diseases. Synthetic tetrapeptide HAEE, or its pharmaceutically acceptable salts, or complexes, or mixtures thereof are used to protect the function of human neurons to secrete substance (4S,7S,10S,13S)-4-((1H-imidazol-4-yl)methyl)-13-carbamoyl-10-(2-carboxyethyl)-7-methyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazagexadecane-16-acid (SRFM).

EFFECT: use of the invention provides the possibility of preventing neurodegenerative disorders and diseases associated with partial or complete loss of SRFM secretion by neurons under the effect of neurotoxic substances, which leads to a significant drop in the level of SRFM secretion in blood compared to the physiological norm.

15 cl, 2 dwg, 9 tbl, 11 ex

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RU 2 822 602 C1

Authors

Kozin Sergej Aleksandrovich

Kopylov Artur Tigranovich

Karpova Evgeniya Mikhajlovna

Yakovlev Ruslan Yurevich

Dates

2024-07-09Published

2023-03-03Filed