NEW VARIANT OF CYTOSINE PERMEASE AND A METHOD FOR PRODUCING l-TRYPTOPHAN WITH ITS USE Russian patent published in 2023 - IPC C12N9/10 C12N15/70 C12P13/22 

Abstract RU 2787791 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. A cytosine permease consisting of an amino acid sequence represented by SEQ ID NO: 1 is proposed, in which isoleucine, which is an amino acid corresponding to position 401 in SEQ ID NO: 3, is replaced by threonine. A polynucleotide encoding said cytosine permease, an Escherichia coli microorganism that produces L-tryptophan and contains said cytosine permease or a polynucleotide encoding said cytosine permease, and a method for producing L-tryptophan are also proposed.

EFFECT: invention makes it possible to increase the yield of L-tryptophan.

5 cl, 1 tbl, 2 ex

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RU 2 787 791 C1

Authors

Park Goun

Chang Jin Sook

Jung Moo Young

Kim Hyun Ah

Bae Jee Yeon

Kim Hyo Jin

Seo Chang Il

Dates

2023-01-12Published

2021-04-19Filed