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(19)

(11)

2 791 193

(13)

(51)

IPC

C12N9/88(2006-01-01)

C12N15/70(2006-01-01)

C12P13/22(2006-01-01)

(21) (22)

Application

2022100411, 2021-04-19

(24)

Start date

2021-04-19

(22)

Actual filing date

2021-04-19

(45)

Published

2023-03-03

(72)

Inventor

Park GounChang Jin SookJung Moo YoungKim Hyun AhBae Jee YeonKim Hyo JinSeo Chang Il

(73)

Holder

Cj Cheiljedang Corporation

NEW FERROCHELATASE VARIANT AND A METHOD TO PRODUCE L-TRYPTOPHAN USING THE FERROCHELATASE Russian patent published in 2023 - IPC C12N9/88 C12N15/70 C12P13/22

Abstract RU 2791193 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and provides a ferrochelatase variant with ferrochelatase activity comprising the amino acid sequence represented by SEQ ID NO: 1, wherein glycine, which is an amino acid corresponding to position 137 in SEQ ID NO: 3, is substituted for asparagic acid. The invention also relates to a method for producing L-tryptophan comprising an Escherichia coli microorganism cultivation in medium, the Escherichia coli contains a ferrochelatase variant or a polynucleotide encoding this variant.

EFFECT: invention makes it possible to obtain L-tryptophan with high efficiency degree.

5 cl, 1 tbl, 2 ex

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RU 2 791 193 C1

Authors

Park Goun

Chang Jin Sook

Jung Moo Young

Kim Hyun Ah

Bae Jee Yeon

Kim Hyo Jin

Seo Chang Il

Dates

2023-03-03—Published

2021-04-19—Filed