FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. A copper-exporting P-type ATPhase A consisting of the amino acid sequence represented by SEQ ID NO: 1 is proposed, in which serine, an amino acid corresponding to position 786 in SEQ ID NO: 3, is substituted for asparagine. A polynucleotide encoding the copper-exporting P-type ATPhase A, an Escherichia coli microorganism, which produces L-tryptophan and contains the copper-exporting P-type ATPhase A or a polynucleotide encoding the copper-exporting P-type ATPhase A, and a method for producing L-tryptophan are also proposed.
EFFECT: invention provides for increasing the L-tryptophan yield.
5 cl, 1 tbl, 2 ex
Authors
Dates
2023-02-27—Published
2021-04-19—Filed