A NEW VARIANT OF H(+)/CL(-) EXCHANGE TRANSPORTER AND A METHOD TO PRODUCE L-TRYPTOPHAN USING THE H(+)/CL(-) EXCHANGE TRANSPORTER Russian patent published in 2023 - IPC C07K14/245 C12N15/70 C12P13/22 

Abstract RU 2790564 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. An H(+)/CL(-) exchange transporter consisting of the amino acid sequence represented by SEQ ID NO: 1 is proposed, in which cysteine, an amino acid corresponding to position 133 in SEQ ID NO: 3, is substituted for phenylalanine. A polynucleotide encoding the H(+)/Cl(-)exchange transporter, an Escherichia coli microorganism, which produces L-tryptophan and contains the H(+)/Cl(-) exchange transporter or a polynucleotide encoding the H(+)/Cl(-)exchange transporter, and a method for producing L-tryptophan are also proposed.

EFFECT: invention provides for increasing the L-tryptophan yield.

5 cl, 1 tbl, 2 ex

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RU 2 790 564 C1

Authors

Park Goun

Chang Jin Sook

Jung Moo Young

Kim Hyun Ah

Bae Jee Yeon

Kim Hyo Jin

Seo Chang Il

Dates

2023-02-27Published

2021-04-19Filed