APTAMERS FOR USE IN INHIBITION AND/OR SUPPRESSION OF TLR9 ACTIVATION Russian patent published in 2023 - IPC C12N15/115 C12N15/117 A61K31/713 A61P25/00 A61P29/00 A61P35/00 A61P37/00 

Abstract RU 2789087 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to aptamers; it can be used in medicine for use in therapy of a subject for inhibition or suppression of TLR9 activation. The used aptamer consists of a nucleic acid sequence SEQ ID No. 1 (GGT TGG TGT GGT TGG).

EFFECT: invention provides inhibition of TLR9 activation in a subject’s cell by specific interaction of an aptamer with TLR9 receptor.

9 cl, 5 dwg, 3 ex

Similar patents RU2789087C2

Title Year Author Number
CPG-OLIGONUCLEOTIDE ANALOGUES, CONTAINING HYDROPHOBIC T-ANALOGUES WITH AMPLIFIED IMMUNOSTIMULATORY ACTIVITY 2007
  • Debelak Kharal'D
  • Ul'Mann Judzhin
  • Jurk Marion
RU2477315C2
IMMUNOSTIMULATING PHOSPHOROTHIOATE CpG-OLIGONUCLEOTIDES, CONTAINING PHOSPHODIESTER LINKS, METHOD OF IMMUNOMODULATION, METHOD OF IMMUNE RESPONSE STIMULATION 2003
  • Krig Artur M.
  • Samulovitts Ul'Rike
  • Foll'Mer Jorg
  • Ul'Mann Ojgen
  • Jurk Marion
  • Lipford Grejson
  • Rankin Robert
RU2338750C2
COMPLEMENT-BINDING APTAMERS AND C5 AGENTS APPLICABLE FOR TREATING OCULAR DISORDERS 2007
  • Ehpshtejn Dehvid
  • Kurts Dzheff S.
RU2477137C2
IMMUNOSTIMULATING G,U-CONTAINING OLYGORIBONUCLEOTIDES 2003
  • Lipford Grehjson B.
  • Bauer Shtefan
  • Vagner Khermann
RU2302865C2
SEMI-SOFT C-CLASS IMMUNOSTIMULATORY OLIGONUCLEOTIDES 2005
  • Krejg Artur M.
  • Zamulovitts Ul'Rike
  • Foll'Mer Jorg
  • Ul'Mann Ojgen
RU2393223C2
VACCINATION USING THE ALPHA 3 DOMAIN OF MICA/B FOR CANCER TREATMENT 2016
  • Wucherpfennig, Kai
  • Badrinath, Soumya
RU2747296C2
COMPLEX CONTAINING AN OLIGONUCLEOTIDE, HAVING IMMUNOSTIMULATING ACTIVITY, AND ITS APPLICATION 2014
  • Isii Ken
  • Kobiyama Koudzi
  • Aosi Taiki
  • Takesita Fumikhiko
  • Kasuya Yudzi
  • Niva Takako
  • Koizumi Makoto
RU2723943C2
COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION 2017
  • Shin Yun Ki
  • Kim Yun Dyu
  • Dzhun Khun Soon
  • Kim Dyuk Ae
RU2664466C1
METHOD OF TUMOUR TREATMENT IN SUBJECT 2006
  • Kong-Beltran Monika
  • Vikramasingkhe Dineli M.
RU2404193C2
IMMUNOSTIMULATING OLIGONUCLEOTIDES 2009
  • Dehvis Khizer Linn
  • Veeratna Risini Dkhammika
RU2477753C2

RU 2 789 087 C2

Authors

Haberland, Annekathrin

Wenzel, Katrin

Dates

2023-01-30Published

2017-10-27Filed