METHOD FOR DIFFERENTIAL DIAGNOSTICS OF LICHEN PLUS OF THE MOUTH MUCOSA Russian patent published in 2023 - IPC G01N33/48 G01N33/52 A61B5/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to therapeutic dentistry and laboratory diagnostics. The mucosa is examined, the buccal epithelium is taken, the ratio of cells with nuclear aberrations, such as a micronucleus, micronucleus protrusions, indicators of the completion of nuclear destruction, such as perinuclear vacuole, karyopyknosis, karyorrhexis, karyolysis and indicators of nuclear proliferation in the form of a notch, the total occurrence of all disorders in buccal epithelium cytogram. In unstimulated oral fluid, pH and light sum of radiation are determined for 5 minutes of chemiluminescence, bacteriological inoculation of smears from the surface of the mucous membrane with the presence of papules and erosive-ulcerative elements is carried out and the content of yeast-like fungi of the genus Candida in yeast or mycelial form is determined, autofluorescent stomatoscopy of the mucous membrane is performed. Depending on the values of these indicators, a typical asymptomatic form of lichen planus or an erosive-ulcerative form of lichen planus or an exudative-hyperemic form of lichen planus is diagnosed.

EFFECT: use of the invention improves the accuracy of diagnosis.

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