ANTICANCER COMPOSITION Russian patent published in 2023 - IPC A61K31/155 A61K31/683 A61K31/7004 A61P35/00 

Abstract RU 2789245 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to the treatment of cancer. The use of a combination is disclosed, where the combination contains: metformin or phenformin, or their pharmaceutically acceptable salt; 2-deoxy-D-glucose; inositol hexaphosphate or its pharmaceutically acceptable salt, inositol, or a mixture thereof, for the production of a drug for the treatment of cancer. In this case, the mass ratio of metformin or its pharmaceutically acceptable salt : 2-deoxy-D-glucose : inositol hexaphosphate or its pharmaceutically acceptable salt, or inositol is from 1:0.2:0.5 to 1:5:20, phenformin or its pharmaceutically acceptable salt : 2-deoxy-D-glucose : inositol hexaphosphate or its pharmaceutically acceptable salt or inositol is from 1:1:1 to 1:50:200, metformin or its pharmaceutically acceptable salt : 2-deoxy-D-glucose : inositol hexaphosphate or its pharmaceutically acceptable salt : inositol is from 1:0.2:0.5:0.5 to 1:5:20:20, or phenformin or its pharmaceutically acceptable salt : 2-deoxy-D-glucose : inositol hexaphosphate or its pharmaceutically acceptable salt : inositol is from 1:1:1:1 to 1:50:200:200. A method for the treatment of cancer, the use for the treatment of cancer of a pharmaceutical composition, and a combination for the treatment of cancer are also disclosed.

EFFECT: group of inventions provides a synergetic anticancer effect.

12 cl, 12 dwg, 9 ex

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RU 2 789 245 C2

Authors

Su, Man-Chkhul

Dzhon, Iyn

Kim, Yn Chi

Dzhon, Chzhe In

Dates

2023-01-31Published

2019-11-11Filed