BILE ACIDS AND BIGUANIDES AS INHIBITORS OF PROTEASES FOR PRESERVATION OF PEPTIDE INTEGRITY IN ALIMENTARY CANAL Russian patent published in 2014 - IPC A61K31/575 A61K31/155 C07J9/00 C07J41/00 A61K38/12 A61P1/00

Abstract RU 2525290 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to methods of preserving integrity of peptides in alimentary canal by application of chenodeoxycholic acid, ursodeoxycholic acid, glydeoxycholic acid, glycochenodeoxycholic acid or biguanide, which inhibit one or more serine proteases of intestine.

EFFECT: preservation of peptide integrity.

27 cl, 16 dwg, 13 ex

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RU 2 525 290 C2

Authors

N'Ju Rodzher R.S.

Trehvers Glen

Dates

2014-08-10—Published

2009-10-01—Filed