COMPOSITION INHIBITING TUMOR GROWTH AND SURVIVAL RATE Russian patent published in 2019 - IPC A61K31/7004 A61K31/7008 A61P35/00 

Abstract RU 2707554 C1

FIELD: biology.

SUBSTANCE: invention relates to molecular biology and is a composition for growth inhibition and tumor cell survival comprising 2-amino-2-deoxy-D-glucose (glucosamine D) and 2-deoxy-D-glucose (2-DG), wherein concentration of 2-amino-2-deoxy-D-glucose (glucosamine D) and 2-deoxy-D-glucose (2-DG) is equal to 3–10 mM for each component, respectively, and the ratio of components is equal to 1:1.

EFFECT: use of the declared invention enables higher stability of the composition, provides high selectivity with respect to tumor cells due to combined effect on tumor cells and higher inhibition of proliferation.

1 cl, 7 dwg, 1 ex

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RU 2 707 554 C1

Authors

Gilyano Nadezhda Yakovlevna

Stepanov Sergej Ivanovich

Dubotolova Mariya Mikhajlovna

Ibatullin Farid Minikasimovich

Dates

2019-11-28Published

2019-02-27Filed