FIELD: biology.
SUBSTANCE: invention relates to molecular biology and is a composition for growth inhibition and tumor cell survival comprising 2-amino-2-deoxy-D-glucose (glucosamine D) and 2-deoxy-D-glucose (2-DG), wherein concentration of 2-amino-2-deoxy-D-glucose (glucosamine D) and 2-deoxy-D-glucose (2-DG) is equal to 3–10 mM for each component, respectively, and the ratio of components is equal to 1:1.
EFFECT: use of the declared invention enables higher stability of the composition, provides high selectivity with respect to tumor cells due to combined effect on tumor cells and higher inhibition of proliferation.
1 cl, 7 dwg, 1 ex
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Authors
Dates
2019-11-28—Published
2019-02-27—Filed