FIELD: pharmaceuticals.
SUBSTANCE: group of inventions relates to the field of organic chemistry and includes 2-([{4-nitrophenyl}imino](phenyl)methyl)isoindoline-1,3-dione by the formula I, a method for production thereof, and an analgesic agent. Method for production is implemented through the reaction of N-(4-nitrophenyl)benzenecarboxymidamide with phthalic acid anhydride. The mixture of N-(4-nitrophenyl)benzenecarboxymidamide with phthalic acid anhydride is boiled without a solvent at a temperature of 250 °C for 30 minutes. The mixture is then cooled, 96% ethanol is added, and the mixture boiled for 15 minutes; the resulting suspension is filtered while hot, the mother solution is cooled and filtered.
EFFECT: production of a compound by the formula I, usable in medicine as a potential analgesic and anti-inflammatory agent.
3 cl, 1 dwg, 5 tbl, 4 ex
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| ANALGESIC AND ANTI-INFLAMMATORY AGENT BASED ON 5-BUTYL-6-HYDROXY-2-METHYL PYRIMIDINE-4(3H)-ONE | 2015 |
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