FIELD: organic and medicinal chemistry.
SUBSTANCE: invention relates to 1,3-dioxo-N,N'-diphenylisoindoline-2-carboximidamide of formula I. The invention also relates to a method of producing a compound of formula I and an analgesic agent based on it. The method of obtaining 1,3-dioxo-N,N'-diphenylisoindoline-2-carboximidamide of formula I is performed by boiling a mixture of diphenylguanidine and phthalic anhydride at a molar ratio of 1:1.2, respectively, in toluene for 2 hours, with solvent distilled off, and the residue of the target product recrystallized from acetone.
EFFECT: 1,3-dioxo-N,N'-diphenylisoindoline-2-carboximidamide compound with analgesic activity.
3 cl, 2 dwg, 3 tbl, 3 ex
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Authors
Dates
2023-07-31—Published
2022-05-30—Filed