ENTERIC CAPSULES OF SOFT GELATIN Russian patent published in 2023 - IPC A61K9/48 

FIELD: pharmaceutics.

SUBSTANCE: invention relates to enteric capsules of soft gelatin. An enteric capsule of soft gelatin for oral administration contains filling material and a shell composition. Moreover, filling material contains at least one pharmaceutically active ingredient. The shell composition contains from 40 to 80 wt.% of gelatin, from 2.0 to 20 wt.% of low-molecular methoxypectin, from 0.15 to 4.0 wt.% of a cellulose derivative, and from 15 to 40 wt.% of a plasticizer. The cellulose derivative is selected from hydroxypropylmethylcellulose, methylcellulose, hydroxypropylcellulose, and a combination thereof. The proposed method for the manufacture of an enteric capsule of soft gelatin includes obtainment of filling material and encapsulation of filling material, using a composition of an enteric shell.

EFFECT: invention provides obtainment of a product with satisfactory enteric characteristics in the absence of the need for application of enteric coating or inclusion of common enteric polymer.

19 cl, 6 tbl, 4 ex