FIELD: experimental pharmacology.
SUBSTANCE: invention relates to experimental pharmacology, namely to a method for creating an experimental model of Parkinson’s disease. For this purpose, mice are once subcutaneously injected with a type 2 monoamine vesicular transporter inhibitor tetrabenazine at a dosage of 12 mg per 1 animal.
EFFECT: invention makes it possible to more accurately reproduce pathological processes in Parkinson’s disease, which in the future may create conditions for the development of a fundamentally new class of antiparkinsonian drugs.
1 cl, 3 dwg, 5 tbl
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Authors
Dates
2023-02-10—Published
2022-03-01—Filed