FIELD: medicine.
SUBSTANCE: invention relates to low-molecular potentiators of potassium channels (such as Kv7 potentiators also called KCNQ potentiators) of the formula 
where R1 is 
or 
, R2 is H or OH, compositions including such compounds, and methods for the use of such compounds for the treatment of amyotrophic lateral sclerosis and other neurological diseases caused by changes in excitability of motor neurons, for example, such as primary lateral sclerosis, pseudobulbar paralysis, progressive bulbar paralysis, progressive muscular atrophy, and epilepsy.
EFFECT: obtainment of compounds for the treatment of neurological diseases.
25 cl, 4 tbl, 3 ex
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