FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new cyclic amine derivatives possessing EP4 receptor antagonist activity, methods for producing them, pharmaceutical compositions containing these compounds, and using them as medicinal products for treating or relieving prostaglandin E mediated diseases, such as acute or chronic pain, osteoarthritis, inflammation-related disorders, such as arthritis, rheumatoid arthritis, malignant new growth, migraine and endometriosis.
EFFECT: producing the compositions for treating or relieving the prostaglandin E mediated diseases.
29 cl, 2 tbl, 47 ex
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