FIELD: biotechnology.
SUBSTANCE: invention represents a bacterium Streptomyces fungicidicus containing one or more modified genes selected from the group consisting of an enhanced open reading frame-24 (orf24) with SEQ ID NO: 38, a weakened open reading frame-18 (orf18) with SEQ ID NO: 37, and also an enhanced orf24 with SEQ ID NO: 38 and a weakened orf18 with SEQ ID NO: 37. The invention also relates to a process for the production of enduracidin, which involves the cultivation of such a bacterium Streptomyces fungicidicus under conditions sufficient for the production of enduracidin.
EFFECT: high enduracidin yield.
17 cl, 12 dwg, 2 tab, 7 ex
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