FIELD: chemistry.
SUBSTANCE: present invention relates to a method for the production of an alpha-hydroxy compound of the formula (I) as a reaction product, where R is -H or -CH3; R' is -CH3, -CH2CH3, -CH(CH3)2, -C6H5, -CH2SCH3, -C8H6N, or -C3H3N2; and R" is -H, -CH3, -CH2CH3, -CH(CH3)2, -CH2CH2CH3, -CH2CH2CH2CH3, -CH2CH(CH3)2, or -C(CH3)3. This method includes following stages: a) provision of the first compound of the formula II: ; b) provision of the second compound of the formula III: where R and R' have values as defined above; c) reaction of the first compound with the second compound and R"OH, where R" has values as defined above, in the presence of a catalyst based on Lewis acid. The invention also relates to a method for the production of amino acid, including a stage of amination of an alpha-hydroxy compound of the formula I, obtained using stages a)-c).
EFFECT: obtainment of amino acids and their hydroxy analogues, using methods, which are flexible and suitable for large-scale industrial production.
36 cl, 13 tbl, 6 ex
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Authors
Dates
2023-02-27—Published
2019-01-23—Filed