METHOD FOR PRODUCTION OF ALPHA-HYDROXY COMPOUNDS AND THEIR USE Russian patent published in 2023 - IPC C07C51/16 C07C51/00 C07C67/39 C07C67/00 C07C59/01 C07C59/48 C07C69/675 C07C69/732 C07C319/12 C07C323/52 C07D209/12 C07D233/64 C07C227/08 C07C227/12 

Abstract RU 2790572 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a method for the production of an alpha-hydroxy compound of the formula (I) as a reaction product, where R is -H or -CH3; R' is -CH3, -CH2CH3, -CH(CH3)2, -C6H5, -CH2SCH3, -C8H6N, or -C3H3N2; and R" is -H, -CH3, -CH2CH3, -CH(CH3)2, -CH2CH2CH3, -CH2CH2CH2CH3, -CH2CH(CH3)2, or -C(CH3)3. This method includes following stages: a) provision of the first compound of the formula II: ; b) provision of the second compound of the formula III: where R and R' have values as defined above; c) reaction of the first compound with the second compound and R"OH, where R" has values as defined above, in the presence of a catalyst based on Lewis acid. The invention also relates to a method for the production of amino acid, including a stage of amination of an alpha-hydroxy compound of the formula I, obtained using stages a)-c).

EFFECT: obtainment of amino acids and their hydroxy analogues, using methods, which are flexible and suitable for large-scale industrial production.

36 cl, 13 tbl, 6 ex

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RU 2 790 572 C2

Authors

Taarning, Esben

Tolborg, Soren

Martinez Espin, Juan Salvador

Dates

2023-02-27Published

2019-01-23Filed