METHOD FOR OBTAINING A POWDERED STATIONARY PHASE FOR HIGH PERFORMANCE LIQUID CHROMATOGRAPHY AND INSTALLATION FOR ITS IMPLEMENTATION Russian patent published in 2023 - IPC B01J20/283 B01J20/10 B02C15/08 C03B19/10 G01N30/02 

FIELD: physicochemical; chemical analysis.

SUBSTANCE: present invention relates to the field of physicochemical and chemical analysis, namely, to a method for obtaining a powdery stationary phase for high performance liquid chromatography, as well as to an installation for implementing such a method. The method consists in taking quartz sand, grinding it in an attritor to a size of 100 mcm, passing it through a high-frequency induction discharge, mixing it with a colloidal solution of pyrogenic silicon oxide in a ratio of 3/1, the resulting mixture is sprayed in an oven at 1050°C and dried for 4 hours, then the mixture is re-mixed with a colloidal solution of pyrogenic silicon oxide and re-sprayed in an oven and dried, while the re-mixing and drying process is repeated until the particle size is not more than 5 mcm. Installation for the implementation of this method consists of an attritor with an openable outlet at the bottom, while fixed at the beginning of the conveyor belt above it; a conveyor belt passing under the outlet of the attritor, while passing between the cathode and the anode of the high-frequency induction discharge generator, located above the mixer at the same time; a high-frequency induction discharge generator located on the sides of the conveyor belt; a mixer located under the end of the conveyor belt with an openable outlet at the bottom; a pump connecting the outlet of the mixer and the sprayer inside the oven with hoses; sprayer fixed inside the furnace and connected to the pump; furnace, inside which the atomizer is fixed.

EFFECT: development of a method for obtaining a powdered stationary phase for high-performance liquid chromatography, with a porous structure in particles only in the outer layer and a particle size of not more than 5 mcm, as well as independence of the particle size at the outlet from the initial particle size of the raw material.

2 cl, 4 dwg, 1 ex