LYOPHILIZED COMPOSITION OF AN RNA POLYMERASE INHIBITOR FOR THE TREATMENT OF FELINE INFECTIOUS PERITONITIS CAUSED BY FELINE CORONAVIRUS Russian patent published in 2023 - IPC A61K31/185 C12N1/00 

Abstract RU 2791737 C1

FIELD: veterinary medicine.

SUBSTANCE: invention is intended for treatment of feline infectious peritonitis (FIP) caused by feline coronavirus (FCoV). A lyophilized form of a composition for preparing a solution for subcutaneous administration based on the nucleoside analog VS-121354 and Taurine amino acid as active ingredients using a solubilizer sodium betadexsulfobutylate and a pH-adjusting agent is proposed in the following ratio of components wt.%: nucleoside analog VS-121354 or its analogue 2.8–3.8, taurine 6.9–8.5, sodium betadexasulfobutylate 84.55–93.45.

EFFECT: technical result consists in increasing the shelf life and improving the consumer properties of the finished dosage form, reducing the severity of pain syndrome and local irritating reactions to the injection field, increasing the therapeutic efficacy by the synergy of the two active substances.

1 cl, 6 tbl, 5 ex

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RU 2 791 737 C1

Authors

Kolesnikov Nikita Valentinovich

Korotkevich Evgeniia Igorevna

Reshetnev Aleksandr Vladimirovich

Reshetnev Aleksandr Vladimirovich

Dates

2023-03-13Published

2023-02-01Filed