FIELD: biotechnology.
SUBSTANCE: invention relates to the recombinant production of immunogenic protein of feline coronavirus, and can be used in veterinary medicine to obtain a vaccine against feline coronavirus. The following is proposed: a new vaccination strategy based on the use of a prophylactic medicinal product based on the conservative recombinant nucleocapsid protein of feline coronavirus (N-FCoV) with SEQ ID NO.: 2 and a specific adjuvant, which is a mixture of squalane, α-tocopherol (vitamin E) and polysorbate-80, which effectively induces a T-cell response against feline coronavirus.
EFFECT: obtaining recombinant protein for immunization against feline coronavirus.
9 cl, 4 dwg, 5 tbl, 6 ex
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