POTENTIOMETRIC METHOD FOR DETERMINING ANTIOXIDANT CAPACITY WITH 2,2'-DIPHENYL-1-PICRYLHYDRAZIL Russian patent published in 2023 - IPC G01N27/416 C07C205/06 C07C243/22 C07B61/00 

FIELD: medicine.

SUBSTANCE: invention relates to the field of physicochemical analysis methods, in particular - to the analysis of solutions regarding the quantification of the antioxidant capacity. The invention can be used for the analysis of food items and pharmaceutical items and consists in a potentiometric method for determining the antioxidant capacity using 2,2'-diphenyl-1-picrylhydrazyl, characterized by the fact that the initial solution of 2,2'-diphenyl-1-picrylhydrazyl is premixed with a concentration of C_DPPH in a solvent and the analysed solution, into which, after mixing, an electrolyte is added and the potential E₁ is measured, the first additive 2,2'-diphenyl-1-picrylhydrazyl is introduced at the concentration of C'_DPPH and the potential E₂ is measured, the second additive is introduced 2,2'-diphenyl-1-picrylhydrazyl at the concentration of C''_DPPH and the potential E₃ is measured, the antioxidant capacity of the analysed solution AOE_DPPH is determined by solving simultaneous equations. By varying the concentrations of the original DPPH and making successive additions, a significant expansion of the determined concentration ranges and a decrease in the determination error are achieved.

EFFECT: technical result of the invention is a developed potentiometric method, which allows to analyse items with own colour of any intensity.

3 cl, 5 dwg, 3 ex