FIELD: pharmaceutical and food industries.
SUBSTANCE: invention relates to a water-soluble composition based on betulin. Water-soluble composition based on betulin, including solid dispersions of betulin, and water-soluble derivatives of glycyrrhizic acid, selected from glycyrrhizic acid (GA), its sodium salt, dry extract of licorice root, with a GA content of up to 20–25 wt. %, with a mass ratio of betulin and glycyrrhizic acid derivatives of 1:10, respectively, obtained by mechanochemical interaction of betulin and glycyrrhizic acid derivatives.
EFFECT: above composition based on betulin is characterized by increased solubility and transmembrane permeability.
1 cl, 2 dwg, 2 tbl, 2 ex
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