COMPOSITE BIOMATERIAL WITH HEMOSTATIC AND REGENERATIVE ACTIVITY (OPTIONS) Russian patent published in 2023 - IPC A61K38/39 A61K38/01 A61K31/315 A61P7/04 A61P17/02 

FIELD: materials for medical purposes.

SUBSTANCE: invention relates to composite biomaterials with hemostatic and regenerative activity, intended for the treatment of damaged and bleeding organs and tissues. The invention can be used in various fields of medicine, pharmaceuticals and veterinary medicine, for example, to stop bleeding during surgical operations on internal organs, in traumatic injuries of the body, as well as for the concomitant regeneration of damaged organs and tissues. The essence of the claimed technical solution is a composite biomaterial with hemostatic and regenerative activity, cross-linked from collagen polypeptides with an average molecular weight of at least 100,000 daltons and fractions of active peptides with a molecular weight of 3,600 to 10,000 daltons, formed by enzymatic cleavage of collagen polypeptides, in the ratio, wt.%: collagen polypeptides: 90–95; fraction of active peptides: 1–4; excipients: the rest. Composite biomaterial with hemostatic and regenerative activity, cross-linked from collagen polypeptides with an average molecular weight of at least 100,000 daltons, fractions of active peptides with a molecular weight of 3,600 to 10,000 daltons, formed during the enzymatic cleavage of collagen polypeptides, and zinc in the ratio, wt.%: collagen polypeptides: 90–94; fraction of active peptides: 1–4; zinc: not more than 1; excipients: the rest.

EFFECT: obtaining composite biomaterial with hemostatic and regenerative activity.

2 cl, 7 dwg, 4 ex