COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH NLRP ACTIVITY Russian patent published in 2023 - IPC C07D221/16 C07D401/12 C07D409/12 C07D417/12 A61K31/435 A61P35/00 

Abstract RU 2795108 C2

FIELD: medicine; chemistry.

SUBSTANCE: compound of formula AA, where A, B, R1, R2, R3, R6, R7, m, n, o, p are defined in the claims, as well as to its pharmaceutical composition and methods of its use.

EFFECT: compound has an NLRP3 modulating effect and can be used to treat a condition, disease, or disorder in which a decrease or increase in NLRP3 activity is one of the causes of the pathology and/or symptoms and/or progression of the condition, disease, or disorder in a subject.

11 cl, 5 dwg, 80 tbl, 870 ex

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RU 2 795 108 C2

Authors

Ghosh, Shomir

Glick, Gary

Katz, Jason

Roush, William

Seidel, Hans, Martin

Shen, Dong-Ming

Venkatraman, Shankar

Dates

2023-04-28Published

2019-11-11Filed