PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF HEPATITIS, LIVER FIBROSIS AND LIVER CIRRHOSIS, INCLUDING FUSION PROTEINS Russian patent published in 2023 - IPC A61K38/18 A61K47/68 A61P1/16 

Abstract RU 2795548 C2

FIELD: medicine.

SUBSTANCE: use of a pharmaceutical composition and a method for preventing or treating hepatitis, liver fibrosis and/or liver cirrhosis using a fusion protein. The use of a pharmaceutical composition for the prevention or treatment of hepatitis, liver fibrosis and/or liver cirrhosis, where the pharmaceutical composition contains as an effective component a fusion protein in an effective amount, including a mutant fibroblast growth factor 21 (FGF21) protein and an immunoglobulin Fc region. A method for preventing or treating hepatitis, liver fibrosis and/or liver cirrhosis, which includes the step of administering a pharmaceutical composition to a subject, where the pharmaceutical composition contains as an effective component a fusion protein in an effective amount, including a mutant fibroblast growth factor 21 (FGF21) protein and an immunoglobulin Fc region.

EFFECT: effective treatment of hepatitis, liver fibrosis and/or liver cirrhosis.

30 cl, 17 dwg, 10 tbl, 30 ex

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RU 2 795 548 C2

Authors

Hong, Han Na

Kim, Jun Hwan

Choi, Hyun Ho

Kim, Dohoon

Kim, Taewang

Oh, Se Woong

Song, Moo Young

Kim, Jong Gyun

Dates

2023-05-04Published

2017-11-10Filed