CARBAMATE COMPOUND AND THE USE OF A COMPOSITION CONTAINING IT FOR THE PREVENTION, RELIEF OR TREATMENT OF ACUTE STRESS DISORDER OR POST-TRAUMATIC STRESS DISORDER Russian patent published in 2023 - IPC A61K31/41 A61K31/138 A61K31/137 A61K31/4525 A61K45/06 A61P25/00 

FIELD: pharmaceuticals; medicine.

SUBSTANCE: group of inventions is directed to the treatment of acute stress disorder or post-traumatic stress disorder. The use of a carbamate compound, which is (R)-1-(2-chlorophenyl)-2-tetrazol-2-yl)ethyl ester of carbamic acid of the following formula 2 or a pharmaceutically acceptable salt, solvate or hydrate thereof for the prevention, alleviation or treatment acute stress disorder or post-traumatic stress disorder is disclosed. Also a combination for the prevention, alleviation or treatment of acute stress disorder or post-traumatic stress disorder, comprising a therapeutically effective amount of a carbamate compound of formula 2 and a selective serotonin reuptake inhibitor (SSRI) selected from the group consisting of fluoxetine, sertraline, paroxetine, and the use of a carbamate compound of formula 2 for preventing, alleviating, or treating symptoms of post-traumatic stress disorder, and a pharmaceutically acceptable salt thereof are disclosed.

EFFECT: group of inventions provides effective treatment of stress disorder.

10 cl, 5 dwg, 3 ex

Formula (2)